The Kim Lab has over 15 years of experience in research across a variety of topics. We focus on CAH, but also investigate other conditions that affect hormones, growth and development, such as Type 1 Diabetes. ☞ Tap the icons below to see our research!
♥️ Obesity and Cardiovascular risk
- Components of Metabolic Syndrome in Youth With Classical Congenital Adrenal Hyperplasia
- Increased Abdominal Adiposity in Adolescents and Young Adults With Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
- Early Adiposity Rebound in Youth with Congenital Adrenal Hyperplasia Predicts Childhood Obesity and Adiposity in Adolescence
- Weight Loss Due to Topiramate in Adolescent with CAH
- Intima-Media Thickness Is Associated with Androgens in Adolescents/Young Adults with CAH
🦴 Bone Health in CAH
- Bone health in youth with congenital adrenal hyperplasia: abdominal and total adiposity is associated with bone mineral density
- Characterization of children and adolescents with classic CAH who had slowed bone‑age progression and improved height prediction with crinecerfont (Abstract submitted 2026)
🧠 Brain and Behavior
- Food Perceptions and Eating Behavior Differ between Youth with and without Type 1 Diabetes (Manuscript in preparation)
- Dietary Decision-Making Differs with Glycemia in Youth with Type 1 Diabetes (Manuscript in preparation)
- Decreased gross motor, working memory, and adaptive behavior in children with congenital adrenal hyperplasia (Manuscript in Review)
- Glucocorticoid dose and type are associated with depression scores in youth with classical congenital adrenal hyperplasia
- Impaired Dietary Decision-Making in Children and Adolescents with Congenital Adrenal Hyperplasia
- Triple trouble: a case of congenital adrenal hyperplasia, Turner syndrome, and autism (Abstract)
- Multicenter study of executive function in congenital adrenal hyperplasia: inverse relationship to age and androgen (Abstract) — Presented at WRMC Joint Plenary 2025 by Dr. Yamashita
- Cognitive performance in classical congenital adrenal hyperplasia: multicenter analysis of age, glucocorticoid dose, and genotype severity (Abstract)
- Cognitive function worsens with increasing age and glucocorticoid dose in classical congenital adrenal hyperplasia due to 21‑hydroxylase deficiency (Abstract) — Poster presented at JCE 2025 by Dr. Yamashita
- Inhibitory control worsens with age and severity in youth and young adults with CAH (Abstract) — Oral presentation by Dr. Yamashita at WRMC 2025
- Neural Correlates of Obesity and Inflammation in Children and Adolescents with Congenital Adrenal Hyperplasia
- Infants with Congenital Adrenal Hyperplasia Exhibit Thalamic Discrepancies in Early Brain Structure
- Altered Emotion Perception Linked to Structural Brain Differences in Youth With Congenital Adrenal Hyperplasia
- Congenital Adrenal Hyperplasia and Brain Health: A Systematic Review of Structural, Functional, and Diffusion Magnetic Resonance Imaging (MRI) Investigations
- Prefrontal Cortex and Amygdala Subregion Morphology Are Associated with Obesity and Dietary Self-control in Children and Adolescents
- Gray Matter Brain Differences in Youth with CAH
- White Matter Brain Differences in Youth with CAH
- Developmental Changes in Food Perception and Preferences
- Brain Subregion Morphology Associated with Obesity and Dietary Self-Control
💊 Clinical Trials
- Long‑term crinecerfont treatment reduced adrenocorticotropic hormone and 17‑hydroxyprogesterone and improved clinical outcomes in children and adolescents with classic congenital adrenal hyperplasia: 2‑year results from CAHTALYST™ pediatric
- Crinecerfont allows for more physiologic glucocorticoid treatment with greater reductions in androstenedione in pediatric patients with classic congenital adrenal hyperplasia: analyses of individual patient data from the CAHtalyst™ pediatric study (Abstract) — Poster presentation by Dr. Geffner
- Crinecerfont reduces plasma adrenocorticotropic hormone and serum 17‑hydroxyprogesterone levels in children and adolescents with classic congenital adrenal hyperplasia: 1‑year results from the CAHtalyst™ pediatric study (Abstract) — Poster presentation by Dr. Geffner
- Evaluation of potential drug‑drug interactions with crinecerfont (Abstract) — Poster presentation by Dr. Auchus
- Glucocorticoid dosing in children and adults with congenital adrenal hyperplasia (Abstract) — Poster presentation by Dr. Khattab
- Crinecerfont maintains reductions in serum androstenedione levels and glucocorticoid doses in children and adolescents with classic congenital adrenal hyperplasia: 1‑year results from the CAHtalyst™ pediatric study (Abstract) — Poster presentation by Dr. Newfield
- Crinecerfont maintains reductions in serum androstenedione levels and glucocorticoid doses in children and adolescents with classic congenital adrenal hyperplasia: 1‑year results from the CAHtalyst™ pediatric study (Abstract) — Poster presentation by Dr. Jeha
- Crinecerfont allows for more physiologic glucocorticoid treatment with greater reductions in androstenedione in pediatric patients with classic congenital adrenal hyperplasia: analyses of individual patient data from the CAHtalyst™ pediatric study (Abstract)
- Phase 3 Trial of Crinecerfont in Pediatric Congenital Adrenal Hyperplasia
💬 Patient and Caregiver Perspectives
- Patient and Parent Perspectives on Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia
- Experiences and preferences of women with CAH and parents about disclosure of childhood surgery
- Growing up with clitoromegaly: experiences of North American women with congenital adrenal hyperplasia
- Majority of females with a life-long experience of CAH and parents do not consider females with CAH to be intersex
- Patients’ and Caregivers’ Attitudes toward ‘Disorders of Sex Development’ Nomenclature
👶 Infants with CAH
- Electrolyte abnormalities and stress dosing predict illness-related hospitalizations among infants and toddlers with congenital adrenal hyperplasia
- Decreased Adrenomedullary Function in Infants With Classical Congenital Adrenal Hyperplasia
- Low Adrenomedullary Function in Infancy Predicts Acute Illness in CAH
- Absence of Testicular Adrenal Rest Tumors in Newborns, Infants, and Toddlers with CAH
✨ Non-classical CAH
🙂 Face and Body in CAH
- Assessment of Facial Morphologic Features in Patients with Congenital Adrenal Hyperplasia using Deep Learning
- Testicular Adrenal Rest Tumors in Boys and Young Adults
- No difference in 2D:4D between Youth with Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
- Digit ratio (2D:4D) and congenital adrenal hyperplasia (CAH): Systematic literature review and meta-analysis.
📄 Clinical characteristics of CAH and Care Guidelines
Additional CAH Publications of interest:
(CAH care guidelines from the Endocrine Society)
- Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline
- A Pharmacokinetic and Pharmacodynamic Study of Delayed and Extended Release Hydrocortisone (Chronocort™) versus Conventional Hydrocortisone (Cortef) in the Treatment of Congenital Adrenal Hyperplasia
- The Phenotypic Spectrum of Contiguous Deletion of CYP21A2 and Tenascin XB: Quadricuspid Aortic Valve and Other Midline Defects
- Clinical Characteristics of a Cohort of 244 Patients with Congenital Adrenal Hyperplasia
- Cardiovascular disease risk in adult women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
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